When searching this topic there is an overwhelm of information available.
In this blog we look and main function of blood which is the delivery of nutrients, oxygen and the removal of CO2 to all parts of the body, organs and cells. Blood is a complex fluid that consists of several components, including red blood cells, white blood cells, platelets, and plasma. Overall, the main function of blood is to maintain homeostasis in the body by transporting essential substances and helping to regulate body temperature, pH, and electrolyte balance.
Whilst arteries and veins, with architecture specific to an anatomical region, present ample of complexity, the delivery to the actual cells happens at the ‘coalface’, through the microvasculature.
The capillaries have diameters ranging from 0.008-0.01 millimetres and the biophysiological behaviour of the blood flow has many aspects to consider such as viscosity and the hydrodynamic resistance determines the overall blood flow for a given perfusion pressure and the number, size and arrangement of micro vessels, their diameters, and on the viscosity of blood. Red blood cells, the volume, also known as haematocrit, have influence on the apparent viscosity as well as the speed of flow.
The Triphasic algorithm takes these and many more in consideration when calibrating the pump to deliver.
The Team@Triphasic.